US Patent Issued to Celgene on Dec. 2 for "Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith" (California Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,281, issued on Dec. 2, was assigned to Celgene Corp. (Summit, N.J.).

"Substituted 1-oxo-isoindoline-5-carboxamide compounds, compositions thereof, and methods of treatment therewith" was invented by Frans Baculi (San Diego), Katherine Northcote (San Diego), Matthew D. Correa (San Diego), Joshua Hansen (La Jolla, Calif.), Laurie A. Lebrun (San Diego), Chin-Chun Lu (San Diego), Gang Lu (San Diego), Mark A. Nagy (San Diego), Sophie Peng (San Diego) and Sophie Perrin-Ninkovic (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure: wherein R1, R2, R3, R4...