ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,444, issued on Jan. 27, was assigned to Celex Oncology Innovations Ltd. (London).
"Treatment of cancer/inhibition of metastasis" was invented by Mustafa Bilgin Ali Djamgoz (London).
According to the abstract* released by the U.S. Patent & Trademark Office: "Substances and methods are disclosed for reducing or preventing metastatic behaviour in VGSC expressing cancer by the effect of at least reducing the persistent part of the voltage gated sodium channel current without eliminating the transient part. Inhibition of metastatic cell behaviours such as detachability, lateral motility, transverse migration and invasiveness is demonstrated using the known drugs ranolazine and riluzol...