ALEXANDRIA, Va., July 28 -- United States Patent no. 12,693,223, issued on July 28, was assigned to CARL ZEISS MICROSCOPY GMBH (Jena, Germany).

"Method and apparatus for detecting fluorescence signals in a three-dimensional region of a sample" was invented by Thomas Kalkbrenner (Jena, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to a detection method for optical signals in a three-dimensional region of a sample, and a detection method for marked antibodies and/or antigens on a biological surface. In the process, signals with a depth of field that is extended in relation to an original depth of field are captured and evaluated. Also, an apparatus includes an optical element in...