US Patent Issued to Caribou Biosciences on Dec. 9 for "Anti-ROR1 antibody and ROR1-targeting engineered cells" (California Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,264, issued on Dec. 9, was assigned to Caribou Biosciences Inc. (Berkeley, Calif.).

"Anti-ROR1 antibody and ROR1-targeting engineered cells" was invented by Vita Golubovskaya (Pinole, Calif.) and Lijun Wu (Albany, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is directed to a monoclonal mouse or humanized ROR1 antibody, or a single-chain variable fragment (scFv). The present invention is also directed to a mouse or humanized ROR1 chimeric antigen receptor (CAR) comprising from N-terminus to C-terminus: (i) a single-chain variable fragment (scFv) of the present invention, (ii) a transmembrane domain, (iii) at least one co...