ALEXANDRIA, Va., Aug. 12 -- United States Patent no. 12,703,881, issued on Aug. 11, was assigned to CAMBRIDGE ENTERPRISE Ltd. (Cambridge, Great Britain).
"Method for labeling nucleic acid" was invented by Manuel Nappi (Cambridge, Great Britain), Alexandre Hofer (Cambridge, Great Britain), Shankar Balasubramanian (Cambridge, Great Britain) and Matthew J. Gaunt (Cambridge, Great Britain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a method for labeling a nucleic acid comprising N6-methyl adenine. The method comprises forming an alpha-amino radical on the N6-methyl group of N6mAde, and capturing the alpha-amino radical with a radical acceptor comprising a nitrosopyridyl group. The prese...