ALEXANDRIA, Va., June 10 -- United States Patent no. 12,292,493, issued on May 6, was assigned to Bruker Biospin GmbH (Rheinstetten, Germany).

"Method for heteronuclear quantitative determination by NMR spectroscopy, reference substances therefor and method for determining the degree of deuteration of a deuterated compound" was invented by Bernd Willi Karl-Heinz Diehl (Cologne, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are a method for the quantitative determination of an analyte in a test item using a NMR spectrometer, wherein the deuterated solvent used to dissolve the analyte is used as the internal standard, and specific reference substances for use in the method according to the i...