ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,583, issued on May 19, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).
"Methods of purifying proteins using chromatography" was invented by Zhiqiang Chen (Boxborough, Mass.), Xuankuo Xu (Boxborough, Mass.), Sanchayita Ghose (Acton, Mass.) and Zhengjian Li (Sudbury, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides a method of purifying proteins using a combined AEX-CEX chromatography in flow-through mode under an operating condition wherein no automation, engineering control, and/or in-line adjustment is used between the AEX and the CEX. The AEX and CEX (or CEX and AEX) can be connected directly."
The patent w...