US Patent Issued to Bristol-Myers Squibb on March 31 for "1H-pyrrolo[3,2-Cpyridine and 1H-pyrrolo[2,3-Cpyridine derivatives as TLR9 inhibitors for the treatment of fibrosis" (New Jersey, Pennsylvania Inventors)

ALEXANDRIA, Va., March 31 -- United States Patent no. 12,590,091, issued on March 31, was assigned to Bristol-Myers Squibb Co. (Princeton, N.J.).

"1H-pyrrolo[3,2-Cpyridine and 1H-pyrrolo[2,3-Cpyridine derivatives as TLR9 inhibitors for the treatment of fibrosis" was invented by Chunjian Liu (Pennington, N.J.) and Alicia Regueiro-Ren (New Hope, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to 1H-pyrrolo[3,2-c]pyridine and 1H-pyrrolo[2,3-c]pyridine derivatives of formula (I) or a salt thereof. The present compounds are inhibitors of TLR9 and useful in treating preventing, or slowing fibrotic diseases, such as e.g. liver fibrosis, renal fibrosis, biliary fibrosis or pancreatic...