ALEXANDRIA, Va., April 21 -- United States Patent no. 12,606,823, issued on April 21, was assigned to Breeze Bio Inc..
"Modified CPF1 guide RNA" was invented by Kunwoo Lee (South San Francisco, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides a nucleic acid comprising a Cpf1 crRNA, a processing sequence 5' of the Cpf1 crRNA, and an extension sequence 5' of the processing sequence. The invention also provides a composition comprising the nucleic acid, a carrier, and optionally Cpf1. Additionally, the invention provides method of genetically modifying a eukaryotic target cell, comprising contacting the eukaryotic target cell with the nucleic acid or the composition to genetically mo...