ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,841, issued on March 24, was assigned to Breakthrough Pharmaceuticals Inc. (Jiangsu Province, China).

"Tetrahydropyrrolocyclic compound and application thereof" was invented by Wei Wei (Shanghai), Peng Li (Shanghai), Na Gao (Shanghai), Haiying He (Shanghai), Jian Li (Shanghai) and Shuhui Chen (Shanghai).

According to the abstract* released by the U.S. Patent & Trademark Office: "A tetrahydropyrrolocyclic compound as represented by formula (I), a pharmaceutically acceptable salt thereof, and an application thereof in preparation of a drug for treating a disease related to a selective orexin-2 (OX-2) receptor antagonist, wherein the related disease is selected from insomnia and de...