US Patent Issued to BRAINGENE on Jan. 27 for "Destabilising domains for conditionally stabilising a protein" (Swedish Inventors)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,711, issued on Jan. 27, was assigned to BRAINGENE AB (Lund, Sweden).

"Destabilising domains for conditionally stabilising a protein" was invented by Mauno Vihinen (Lund, Sweden) and Deniz Kirik (Lund, Sweden).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure relates to mutant polypeptides derived from Escherichia coli dihydrofolate reductase (DHFR) which can be fused to a polypeptide of interest for efficient conditional modulation of its activity. Also disclosed are polynucleotides encoding such mutant polypeptides, vectors comprising such polynucleotides, and the use of such polypeptides, polynucleotides and vectors for treating...