ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,753,146, issued on Oct. 6, was assigned to BRACCO IMAGING S.P.A. (Milan).
"Industrial synthesis of serinol" was invented by Luciano Lattuada (Cassina de'Pecchi, Italy), Giovanni Battista Giovenzana (Novara, Italy), Camilla Cavallotti (Novara, Italy) and Ivan Menegotto (Borgomanero, Italy).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention is related to the synthesis of 4-hydroxymethyl-2-oxazolidinone (serinol carbamate, SC), which can be subsequently hydrolyzed to 2-amino-1,3-propanediol (serinol), by reacting glycerol and urea: (I) In general, glycerol is heated with urea and a catalyst, with or without a solvent, to give mainly 4-hydro...