ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,124, issued on Sept. 8, was assigned to BOREALIS GMBH (Vienna).

"Medical use of cystic fibrosis transmembrane conductance regulator (CFTR) modulators" was invented by Wolfgang Kubler (Berlin), Lasti Efrinanda Fuaadi (Berlin), Birgitt Gutbier (Berlin) and Martin Witzenrath (Berlin).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a cystic fibrosis transmembrane conductance regulator (CFTR) modulator for use in the prevention and/or treatment of diseases involving endothelial and/or epithelial barrier dysfunctions. The disease does not comprise cystic fibrosis.The invention further relates to a pharmaceutical composition comprisi...