ALEXANDRIA, Va., Nov. 11 -- United States Patent no. 12,465,653, issued on Nov. 11, was assigned to BOLT BIOTHERAPEUTICS INC. (Redwood City, Calif.).

"Thienoazepine immunoconjugates, and uses thereof" was invented by Romas Kudirka (Redwood City, Calif.) and Brian Safina (Redwood City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides immunoconjugates of Formula I comprising an antibody linked by conjugation to one or more thienoazepine derivatives. The invention also provides thienoazepine derivative intermediate compositions comprising a reactive functional group. Such intermediate compositions are suitable substrates for formation of the immunoconjugates through a linker or linki...