ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,715, issued on April 14, was assigned to Boehringer Ingelheim International GmbH (Ingelheim am Rhein, Germany).

"Soluble guanylate cyclate activators for treating systemic sclerosis" was invented by Mary Ruth Flack (New York), Julia Kaufman (Eastchester, N.Y.) and Indra Sethy-Coraci (Ridgefield, Conn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods for treating patients with systemic sclerosis, comprising administering to a patient in need thereof a therapeutically effective amount of a soluble guanylate cyclase (sGC) activator of formula (I),or a pharmaceutically acceptable salt thereof, where R1-R7 and A ar...