ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,742,002, issued on Sept. 22, was assigned to BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (Austin, Texas).
"Engineered T cell receptors and methods of use" was invented by Cassian Yee (Houston) and Ke Pan (Houston).
According to the abstract* released by the U.S. Patent & Trademark Office: "This disclosure provides for engineered T cell Receptors (TCRs), cells comprising the TCRs, and methods of making and using the TCRs. The current disclosure relates to TCRs that specifically recognize cancer testis (CT) antigens of the MAGE-A4 antigen. Accordingly, aspects of the disclosure relate to an engineered T-cell Receptors (TCRs), nucleic acids encoding the TCRs, and cells comprising ...