US Patent Issued to Board of Regents, The University of Texas System on March 3 for "Hybrid exosomal-polymeric (hexpo) nano-platform for delivery of RNAi therapeutics" (Texas Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,564,558, issued on March 3, was assigned to Board of Regents, The University of Texas System (Austin, Texas).

"Hybrid exosomal-polymeric (hexpo) nano-platform for delivery of RNAi therapeutics" was invented by Anil K. Sood (Pearland, Texas), Sherry Y. Wu (Houston) and Gabriel Lopez-Berestein (Houston).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are lipid-based nanoparticles (e.g., exosomes) having (a) a core comprising a cationic polymer and a therapeutic agent (e.g., a therapeutic protein, an antibody, an inhibitory RNA, and/or a small molecule drug) and (b) a lipid coating comprising an exosomes-derived membrane. Furthermore, the pre...