US Patent Issued to Board of Regents, The University of Texas System on Dec. 23 for "Connexin 43 (Cx43) hemichannel-binding antibodies" (Texas Inventors)

ALEXANDRIA, Va., Dec. 23 -- United States Patent no. 12,503,500, issued on Dec. 23, was assigned to Board of Regents, The University of Texas System (Austin, Texas).

"Connexin 43 (Cx43) hemichannel-binding antibodies" was invented by Jean X. Jiang (Helotes, Texas), Zhiqiang An (Houston), Ningyan Zhang (Houston), Wei Xiong (Houston), Manuel A. Riquelme (San Antonio), Sumin Gu (San Antonio) and Naomi Ledene Sayre (San Antonio).

According to the abstract* released by the U.S. Patent & Trademark Office: "Antibodies that bind to connexin 43 hemichannels and inhibit, or activate, channel opening are provided. In certain aspects, methods for detecting or treating cancers with antibodies that activate Cx43 channel opening are also provided. Likew...