ALEXANDRIA, Va., April 15 -- United States Patent no. 12,599,583, issued on April 14, was assigned to Board of Regents, The University of Texas System (Austin, Texas) and Board of Trustees of the University of Arkansas (Little Rock, Ark.).

"Small molecule GRB2 stabilizers for Ras map kinase inhibition" was invented by Zamal Ahmed (Houston), John A. Tainer (Houston) and Darin E. Jones (Little Rock, Ark.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure compounds of the formula (I-A) or (I), wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods for the use of said compounds and/or pharmaceutical compositions, s...