US Patent Issued to BIOVERATIV THERAPEUTICS on July 14 for "Optimized factor VIII gene" (Massachusetts Inventors)

ALEXANDRIA, Va., July 14 -- United States Patent no. 12,679,882, issued on July 14, was assigned to BIOVERATIV THERAPEUTICS INC. (Waltham, Mass.).

"Optimized factor VIII gene" was invented by Siyuan Tan (Lexington, Mass.) and Robert T. Peters (Needham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides codon optimized Factor VIII sequences, vectors and host cells comprising codon optimized Factor VIII sequences, polypeptides encoded by codon optimized Factor VIII sequences, and methods of producing such polypeptides. The present invention also provides methods of treating bleeding disorders such as hemophilia comprising administering to the subject a codon optimized Factor VI...