ALEXANDRIA, Va., Oct. 27 -- United States Patent no. 12,774,340, issued on Oct. 27, was assigned to BIOTHEUS INC. (Zhuhai, China).
"Anti-4-1BB single-domain antibodies, nanobodies, fusion proteins thereof and methods of use thereof for treatment" was invented by Tianhang Zhai (Zhuhai, China), Xiaoniu Miao (Zhuhai, China), Yifeng Xu (Zhuhai, China), Chao Wang (Zhuhai, China) and Andy Tsun (Zhuhai, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Related is a single-domain antibody targeting 4-1BB, a fusion protein thereof, a pharmaceutical composition and a use thereof. Specifically, the related single-domain antibody comprises one heavy chain variable region, and the amino acid sequences of CDR1-CDR3 con...