ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,715,931, issued on Aug. 25, was assigned to BIOSION INC. (Nanjing, China).
"Nanobodies binding TROP2 and uses thereof" was invented by Mingjiu Chen (Nanjing, China) and Mark Zhiqing Ma (Nanjing, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "A heavy chain only antibody that specifically binds human TROP2, or an antigen-binding portion thereof is provided. A nucleic acid molecule encoding the antibody or the antigen-binding portion thereof, an expression vector, a host cell and a method for expressing the antibody or the antigen-binding portion thereof are also provided. Further provided are an immunoconjugate and a pharmaceutical composition compr...