ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,607, issued on May 19, was assigned to BioNTech SE (Mainz, Germany).
"PRAME TCR receptors and uses thereof" was invented by Manon Weis (Sankt Wolfgang, Germany), Patrik Kehler (Planegg, Germany), Maria Gerget (Munich), Christian Krendl (Graefelfing, Germany) and Susanne Wilde (Germering, Germany).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a T cell receptor (TCR) capable of binding to a PRAME peptide having the amino acid sequence SLLQHLIGL (SEQ ID NO: 1) or a portion thereof, or its HLA-A2 bound form. Also encompassed in the present invention is a nucleic acid encoding a TCR, a vector comprising the nucleic acid, a...