US Patent Issued to Biogen MA on Aug. 25 for "Methods for determining differences in alpha-4 integrin activity by correlating differences in sVCAM and/or sMAdCAM levels" (California Inventor)

ALEXANDRIA, Va., Aug. 25 -- United States Patent no. 12,716,899, issued on Aug. 25, was assigned to Biogen MA Inc. (Cambridge, Mass.).

"Methods for determining differences in alpha-4 integrin activity by correlating differences in sVCAM and/or sMAdCAM levels" was invented by Alissa A. Chackerian (Sunnyvale, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein is a method of monitoring the change of the alpha-4 integrin activities in an individual by correlating with the soluble vascular cell adhesion molecule (sVCAM) and/or soluble mucosal addressin cell adhesion molecule (sMAdCAM) levels. Particularly, this method can be used, for example, to evaluate the pharmacokinetics and pharmacodynami...