ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,485,109, issued on Dec. 2, was assigned to BioCryst Pharmaceuticals Inc. (Durham, N.C.).

"Pyrrolo 12.3-dipyrimidine compounds and analogues thereof" was invented by Pravin L. Kotian (Hoover, Ala.), Yarlagadda S. Babu (Birmingham, Ala.), Weihe Zhang (Vestavia Hills, Ala.), Lakshminarayana Vogeti (Lawrence, Kan.), Minwan Wu (Vestavia Hills, Ala.), Venkat R. Chintareddy (Vestavia Hills, Ala.) and Krishnan Raman (Birmingham, Ala.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are compounds of formula I, and pharmaceutically acceptable salts thereof. The compounds are inhibitors of the complement system. Also provided are pharmaceutical compositions...