ALEXANDRIA, Va., April 7 -- United States Patent no. 12,595,592, issued on April 7, was assigned to BioAtla Inc. (San Diego).
"Comprehensive monoclonal antibody generation" was invented by Jay M. Short (JAckson, Wyo.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods for efficiently generating recombinant monoclonal antibodies derived from B cells of a non-human host which has been immunochallenged with one or more target antigens. The methods comprise the steps of identifying and isolating B cell that bind to the antigen by FACS, and recombining and enriching for thousands of cells to create a B cell library. Related products and methods, such as methods of producing exp...