ALEXANDRIA, Va., May 19 -- United States Patent no. 12,630,588, issued on May 19, was assigned to BicycleTx Ltd. (Cambridge, Great Britain).
"Bicyclic peptide ligands specific for CD137" was invented by Liuhong Chen (Cambridge, Great Britain), Rachid Lani (Cambridge, Great Britain), Kevin McDonnell (Lexington, Mass.), Gemma Elizabeth Mudd (Cambridge, Great Britain) and Peter Park (Lincoln, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to polypeptides which are covalently bound to molecular scaffolds such that two or more peptide loops are subtended between attachment points to the scaffold. In particular, the invention describes peptides which are high affinity binders of...