ALEXANDRIA, Va., June 16 -- United States Patent no. 12,655,399, issued on June 16, was assigned to BGI SHENZHEN (Shenzhen, China).
"Stable phi29 DNA polymerase having high enzyme activity, and encoding gene and application thereof" was invented by Yue Zheng (Shenzhen, China), Xun Xu (Shenzhen, China), Wenwei Zhang (Shenzhen, China), Yuliang Dong (Shenzhen, China) and Yujun Zhou (Shenzhen, China).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are a stable Phi29 DNA polymerase having high enzyme activity, and an encoding gene and an application thereof. The Phi29 DNA polymerase is obtained by substituting amino acid residue at at least one among the following 29 positions: position 17, position 96, po...