US Patent Issued to BeOne Medicines | on Oct. 6 for "EGFR degraders and associated methods of use" (Chinese Inventors)

ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,752,012, issued on Oct. 6, was assigned to BeOne Medicines | GmbH (Basel, Switzerland).

"EGFR degraders and associated methods of use" was invented by Bailin Lei (Beijing), Huaqing Liu (Beijing), Songzhe Han (Beijing) and Zhiwei Wang (Beijing).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are novel bifunctional compounds formed by conjugating EGFR inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation. The disclosure also provides pharmaceutically acceptable compositions comprising compounds and methods for the treatment of EGFR mutant-related cancers."

The pa...