ALEXANDRIA, Va., Oct. 6 -- United States Patent no. 12,752,007, issued on Oct. 6, was assigned to Beijing Tiantan Hospital, Capital Medical University (Beijing).
"Inducible chimeric antigen receptor and application thereof" was invented by Jun Xu (Beijing), Yanli Wang (Beijing), Jiwei Jiang (Beijing), Zhongli Du (Beijing) and Zhenlan Du (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "An inducible chimeric antigen receptor and its application relate to the field of immune therapy. The inducible antigen receptor includes a single-chain variable fragment (scFv) antibody against human CSF1R, a truncated hIgG1 hinge region SH, a T cell co-stimulatory signaling molecule, and a T cell cytoplasmic signaling ...