ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,766,193, issued on Oct. 20, was assigned to Beijing Neurosurgical Institute (Beijing).
"Anti-CD133 single-chain antibody and use thereof in preparation of drug for treating tumor" was invented by Wei Zhang (Beijing), Tao Jiang (Beijing), You Zhai (Beijing) and Guanzhang Li (Beijing).
According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to an anti-CD133 single-chain antibody. The amino acid sequence of the anti-CD133 single-chain antibody comprises a sequence shown in SEQ ID NO. 1. T lymphocytes expressing the anti-CD133 single-chain antibody can specifically kill CD133-positive tumor cells and have higher specificity and stronger killing ...