US Patent Issued to BAYER on June 2 for "Enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst" (German, Swiss Inventors)

ALEXANDRIA, Va., June 2 -- United States Patent no. 12,643,860, issued on June 2, was assigned to BAYER AG (Germany).

"Enantioselective hydrogenation of 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium catalyst" was invented by Christoph Schotes (Dusseldorf, Germany), Dirk Eckart Brohm (Mettmann, Germany) and Johannes Schranck (Basel, Switzerland).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention relates to a process for preparing optically active 4-substituted 1,2,3,4-tetrahydroquinolines comprising enantioselective hydrogenation of the corresponding 4-substituted 1,2-dihydroquinolines in presence of a chiral iridium (P,N)-ligand catalyst."

The patent was filed on Sept. 19, 202...