ALEXANDRIA, Va., April 7 -- United States Patent no. 12,594,084, issued on April 7, was assigned to AVVIO Medical Inc. (San Francisco).

"Ultrasound device for use with synthetic cavitation nuclei" was invented by Daniel J. Laser (San Francisco), William Behnke-Parks (San Francisco), David Bell (San Francisco), Matthew Hopcroft (San Francisco) and Kyle P. Morrison (Bothell, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates generally to an ultrasound device configured to generate a frustum-shaped beam capable of fragmenting a plurality of biomineralizations located within a patient's body in combination with synthetic cavitation nuclei. The ultrasound device includes a transducer asse...