US Patent Issued to AUSPERBIO THERAPEUTICS on March 3 for "Oligonucleotides comprising segmented gap structures" (California Inventors)

ALEXANDRIA, Va., March 3 -- United States Patent no. 12,565,651, issued on March 3, was assigned to AUSPERBIO THERAPEUTICS INC. (Foster City, Calif.).

"Oligonucleotides comprising segmented gap structures" was invented by Guofeng Cheng (Foster City, Calif.) and Cheng Yong Yang (Foster City, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are modified oligonucleotides complementary to a portion of a Hepatitis B virus (HBV) genome, wherein the modified oligonucleotides comprise a 5' wing segment, a first gap segment, a first separator segment comprising a 2' sugar modification, a second gap segment, and a 3' wing segment. Such modified oligonucleotides are useful to treat, prevent, or am...