ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,466, issued on Dec. 16, was assigned to aTyr Pharma Inc. (San Diego) and Pangu BioPharma Ltd. (Hong Kong).

"Compositions and methods comprising histidyl-tRNA synthetase splice variants having non-canonical biological activities" was invented by Jie Zhou (Hong Kong), Ching-Fun Lau (Hong Kong), Zhiwen Xu (San Diego), Wing-Sze Lo (Hong Kong), Kristi Helen Piehl (San Diego) and Leslie Ann Greene (San Diego).

According to the abstract* released by the U.S. Patent & Trademark Office: "Isolated histidyl-tRNA synthetase splice variant polynucleotides and polypeptides having non-canonical biological activities are provided, as well as compositions and methods related thereto."

The patent...