US Patent Issued to Astrin Biosciences on Sept. 8 for "Trojan circulating tumor cells" (Minnesota Inventor)

ALEXANDRIA, Va., Sept. 8 -- United States Patent no. 12,728,140, issued on Sept. 8, was assigned to Astrin Biosciences Inc. (St. Paul, Minn.).

"Trojan circulating tumor cells" was invented by Jayant Parthasarathy (Excelsior, Minn.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are compositions and methods for engineering treatment resistant circulating tumor cells to generate immune stimulating or anti-cancer exosomes, which can be infused into a patient to self-home to the primary tumor and metastatic lesions. Also provided are compositions and methods for forming a population of engineered exosome-loaded dendritic cells, which can be infused into the patient to activate a systemic immune re...