US Patent Issued to ARUMUGAVADIVEL NARENDRAN on Sept. 22 for "Small molecule LIN28 inhibitors as anticancer agents" (Canadian Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,987, issued on Sept. 22, was assigned to ARUMUGAVADIVEL NARENDRAN (Calgary, Canada).

"Small molecule LIN28 inhibitors as anticancer agents" was invented by Arumugavadivel Narendran (Calgary, Canada) and Mohit Jain (Calgary, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "LIN28 is an RNA binding protein that binds and inhibits the expression and maturation of Iet7 microRNA that carries key tumor suppressor functions. Thus, LIN28 is a feasible and effective molecular target for directed inhibition with the potential to provide therapeutic benefit to a diverse group of aggressive malignancies. The present disclosure relates generally to the Rati...