US Patent Issued to Arizona Board of Regents on Behalf of the University of Arizona on Dec. 2 for "Small molecule inhibitors of CaV3.2 activity and uses thereof" (Arizona Inventors)

ALEXANDRIA, Va., Dec. 2 -- United States Patent no. 12,486,257, issued on Dec. 2, was assigned to Arizona Board of Regents on Behalf of the University of Arizona (Tucson, Ariz.).

"Small molecule inhibitors of CaV3.2 activity and uses thereof" was invented by Jun Wang (Tucson, Ariz.) and Rajesh Khanna (Tucson, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention is in the field of medicinal chemistry. In particular, the invention relates to a new class of small-molecules having a piperazine or piperidine structure which function as inhibitors of the CaV3.2 voltage gated calcium channel activity (e.g., depolarization-induced calcium influx), and their use as therapeutics for the treatment and/or...