ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,747,432, issued on Sept. 29, was assigned to ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (Scottsdale, Ariz.).

"Modulating human Cas9-specific host immune response" was invented by Radwa Ewaisha (Tempe, Ariz.), Samira Kiani (Scottsdale, Ariz.), Shayesteh Roshdi Ferdosi (Tempe, Ariz.), Karen Anderson (Scottsdale, Ariz.), Farzaneh Moghadam (Tempe, Ariz.), Sri Krishna (Tempe, Ariz.) and Mo Reza Ebrahimkhani (Scottsdale, Ariz.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are methods and compositions for reducing an undesirable T cell immune response in human patients prior to and/or during gene therapy using CRISPR/Cas9-...