ALEXANDRIA, Va., May 26 -- United States Patent no. 12,638,453, issued on May 26, was assigned to ARACLON BIOTECH S.L. (Saragossa, Spain).
"Methods for quantification of amyloid Beta peptides in plasma by mass spectrometry" was invented by Jose Antonio Allue Blasco (Saragossa, Spain) and Maria Leticia Sarasa Coronas (Saragossa, Spain).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to a method for preparing a plasma sample comprising amyloid beta peptides for analysis by mass spectrometry, comprising the steps of:a) contacting said plasma sample with a denaturing agent, b) performing a first solid phase extraction step on the solution obtained in step a) to recover a first eluate,...