ALEXANDRIA, Va., March 24 -- United States Patent no. 12,583,860, issued on March 24, was assigned to Apotex Inc. (Toronto).

"Processes for the preparation of multicomponent crystalline forms of active pharmaceutical ingredients using solvent vapour" was invented by Alexander J. Stirk (Dartmouth, Canada), Fabio E. S. Souza (Mississauga, Canada), Avedis Karadeolian (Brantford, Canada), Allan W. Rey (Toronto) and Fatemeh Mohammadpourmir (Canton, Mich.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides solvent-limited processes for the preparation of an existing crystalline solid form of an active pharmaceutical ingredient comprising mixing, in the presence of solvent vapour, of a sol...