ALEXANDRIA, Va., Sept. 17 -- United States Patent no. 12,416,029, issued on Sept. 16, was assigned to Antheia Inc. (Menlo Park, Calif.).

"Compositions and methods for making benzylisoquinoline alkaloids, morphinan alkaloids, thebaine, and derivatives thereof" was invented by Peter James Facchini (Calgary, Canada), Xue Chen (Calgary, Canada), Jeffrey C. Colbeck (Davis, Calif.) and Joseph E. Tucker (Strathmore, Canada).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein are methods that may be used for the synthesis of benzylisoquinoline alkaloids ("BIAs") such as alkaloid morphinan. The methods disclosed can be used to produce thebaine, oripavine, codeine, morphine, oxycodone, hydrocodone, oxymorph...