ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,746,306, issued on Sept. 29, was assigned to AMTIXBIO Co. LTD. (Seoul, South Korea).
"Hyaluronic acid derivative and use thereof" was invented by Seung Woo Cho (Seoul, South Korea), Jung-Seung Lee (Seoul, South Korea), Jung Ho Cho (Seoul, South Korea) and Jong-Seung Lee (Seoul, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides a hydrogel platform using, as a substrate, hyaluronic acid (HA) conjugated to a pyrogallol (PG) moiety. The HA-PG conjugate of the present invention can be rapidly crosslinked by two different methods, in each of which an oxidizing agent is used or a pH is adjusted. The hydrogel of the pres...