US Patent Issued to Amgen on Sept. 22 for "Methylation of Mcl-1 compounds" (California, Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 24 -- United States Patent no. 12,741,977, issued on Sept. 22, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Methylation of Mcl-1 compounds" was invented by Michal Achmatowicz (San Diego), Sheng Cui (Lexington, Mass.), Tsang-Lin Hwang (Camarillo, Calif.), Neil Fred Langille (Sudbury, Mass.), Janine K. Tom (Thousand Oaks, Calif.), James E. Huckle (Moorpark, Calif.), Markian Stec (Moorpark, Calif.), Tian Wu (Newbury Park, Calif.) and Sean P. Brown (Half Moon Bay, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed herein is an improved process for the synthesis of compound (A): (A), or a salt or solvate thereof via methylation of compound (B): (B), or a salt or solvate...