ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,536, issued on Sept. 2, was assigned to Amgen Inc. (Thousand Oaks, Calif.).
"Detection assay for protein-polynucleotide conjugates" was invented by Mai Thayer (Alameda, Calif.) and Sara Humphreys (Oakland, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to methods for detecting and quantifying intact protein-polynucleotide conjugate molecules in various sample matrices. In particular, the methods utilize triplex forming oligonucleotides in combination with protein-specific binding partners to respectively detect the polynucleotide and protein components of the conjugate molecules."
The patent was filed on Nov. 29...