US Patent Issued to Amgen on April 14 for "Interleukin-2 muteins for the expansion of T-regulatory cells" (California Inventors)

ALEXANDRIA, Va., April 15 -- United States Patent no. 12,600,758, issued on April 14, was assigned to Amgen Inc. (Thousand Oaks, Calif.).

"Interleukin-2 muteins for the expansion of T-regulatory cells" was invented by Darren L. Bates (Oak Park, Calif.), Sue J. Sohn (Daly City, Calif.), Hannah Beth Catterall (Santa Monica, Calif.) and Zhulun Wang (Los Altos, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are IL-2 muteins and IL-2 mutein Fc fusion molecules that preferentially expand activate cells and are amenable to large scale production. Also provided herein are methods of making and using the compositions of the present invention."

The patent was filed on Aug. 13, 2020, under Appli...