ALEXANDRIA, Va., July 28 -- United States Patent no. 12,692,299, issued on July 28, was assigned to Alpine Immune Sciences Inc. (Seattle).
"Variant ICOS ligand immunomodulatory proteins and related compositions and methods" was invented by Lawrence Evans (Seattle), Michael Kornacker (Seattle) and Ryan Swanson (Seattle).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are immunomodulatory proteins comprising ICOSL variants and nucleic acids encoding such proteins. The immunomodulatory proteins provide therapeutic utility for a variety of immunological and oncological conditions. Compositions and methods for making and using such proteins are provided."
The patent was filed on Feb. 21, 2023, unde...