US Patent Issued to Alnylam Pharmaceuticals on Sept. 2 for "Ketohexokinase (KHK) iRNA compositions and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Sept. 3 -- United States Patent no. 12,404,508, issued on Sept. 2, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Ketohexokinase (KHK) iRNA compositions and methods of use thereof" was invented by Leila Noetzli (Boston), James D. McIninch (Burlington, Mass.), Frederic Tremblay (Boston), Mark K. Schlegel (Boston) and Adam Castoreno (Framingham, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to RNAi agents, e.g., dsRNA agents, targeting the ketohexokinase (KHK) gene. The invention also relates to methods of using such RNAi agents to inhibit expression of a KHK gene and to methods of treating or preventing a KHK-associated disorder in a sub...