US Patent Issued to Alnylam Pharmaceuticals on Aug. 18 for "Huntingtin (HTT) iRNA agent compositions and methods of use thereof" (Massachusetts Inventors)

ALEXANDRIA, Va., Aug. 18 -- United States Patent no. 12,709,748, issued on Aug. 18, was assigned to Alnylam Pharmaceuticals Inc. (Cambridge, Mass.).

"Huntingtin (HTT) iRNA agent compositions and methods of use thereof" was invented by Mangala Meenakshi Soundarapandian (Cambridge, Mass.), James D. McIninch (Burlington, Mass.), Bret Lee Bostwick (Cambridge, Mass.), Mark K. Schlegel (Boston), Adam Castoreno (Framingham, Mass.) and Jeffrey Zuber (Somerville, Mass.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The disclosure relates to double stranded ribonucleic acid (dsRNAi) agents and compositions targeting a Huntingtin (HTT) gene, e.g., exon 1 of an HTT gene, as well as methods of inhibiting expression of an...