ALEXANDRIA, Va., Feb. 11 -- United States Patent no. 12,544,481, issued on Feb. 10, was assigned to ALEO BME Inc. (State College, Pa.).

"Water-based tissue adhesives" was invented by Chao Liu (State College, Pa.), Jinshan Guo (State College, Pa.), Chen Chen (State College, Pa.), John Jay Round (State College, Pa.) and Wei Song (State College, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "An adhesive composition described herein comprises an aqueous solvent; and a population of first nanoparticles dispersed in the aqueous solvent, the first nanoparticles comprising a negative or positive charge, and an average size in three dimensions of 1 nm to 1000 nm. In some embodiments, a population of second nanopa...